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Dosing and Administration
Not an actual patient. Individual results will vary.
ILARIS is given subcutaneously by a health care professional in two steps1
Once a month in FMF, HIDS/MKD, and TRAPS1
| Body Weight | Recommended Dose | If the Clinical Response Is Not Adequate |
| ≤40 kg | 2 mg/kg every 4 weeks | the dosage can be increased to 4 mg/kg every 4 weeks |
| >40 kg | 150 mg every 4 weeks | the dosage can be increased to 300 mg every 4 weeks |
Once every 2 months in CAPS: FCAS and MWS1
| Body Weight | Recommended Dose | For Pediatric Patients With Inadequate Response |
| ≥15 kg to ≤40 kg | 2 mg/kg every 8 weeks | For pediatric patients with an inadequate response, the dosage can be increased to 3 mg/kg every 8 weeks |
| >40 kg | 150 mg every 8 weeks |
Step 1: Inspect
ILARIS solution has a concentration of 150 mg/mL - DO NOT SHAKE.
The solution should be:
- Essentially free from particulates
- Clear to opalescent
- Colorless to slightly brownish-yellow tint
DO NOT USE if the solution:
- Has a distinctly brown discoloration
- Is highly opalescent
- Contains visible particles
Step 2: Inject
Using a sterile 1-mL syringe and 18-gauge x 2” needle, carefully withdraw the required volume depending on the dose to be administered and subcutaneously inject using a 27-gauge x 0.5” needle.
Avoid injection into scar tissue as this may result in insufficient exposure to ILARIS.
Discard unused product or waste material in accordance with the local requirements.
ILARIS Dosing Guide
Download the Dosing Guide to view additional important information about administering ILARIS.
Refer to the full Prescribing Information for detailed preparation and administration instructions.
Reference: 1. Ilaris. Prescribing information. Novartis Pharmaceuticals Corp.
Reference: 1. Ilaris. Prescribing information. Novartis Pharmaceuticals Corp.